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1

Prodrug-based design, synthesis, and biological evaluation of N-benzenesulfonylpiperidine derivatives as novel, orally active factor Xa inhibitors

Tsukasa Ishihara, Norio Seki, Fukushi Hirayama, Masaya Orita, Hiroyuki Koshio, Yuta Taniuchi, Yumiko Sakai-Moritani, Yoshiyuki Iwatsuki, Seiji Kaku, Tomihisa Kawasaki, Yuzo Matsumoto, Shin-ichi Tsukam

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 1.31 MB

english, 2007

2

Epitopes and nuclear localization analyses of canine distemper virus nucleocapsid protein by expression of its deletion mutants

Emi Yoshida, Yeon-Sil Shin, Kiyoko Iwatsuki, Tsuyoshi Gemma, Naoko Miyashita, Keizo Tomonaga, Norio Hirayama, Takeshi Mikami, Chieko Kai

Journal:

Veterinary Microbiology

Year:

1999

Language:

english

File:

PDF, 140 KB

english, 1999

3

Antigenic differences in the H proteins of canine distemper viruses

Kiyoko Iwatsuki, Sachio Tokiyoshi, Norio Hirayama, Kazuya Nakamura, Kenjiro Ohashi, Chiaki Wakasa, Takeshi Mikami, Chieko Kai

Journal:

Veterinary Microbiology

Year:

2000

Language:

english

File:

PDF, 114 KB

english, 2000

4

Adenosine potentiates secretin-stimulated pancreatic exocrine secretion in the dog

Fujio Yamagishi, Norio Homma, Kohichi Haruta, Kazuhiko Iwatsuki, Shigetoshi Chiba

Journal:

European Journal of Pharmacology

Year:

1985

Language:

english

File:

PDF, 471 KB

english, 1985

5

Discovery of N -[2-Hydroxy-6-(4-methoxybenzamido)phenyl]-4- (4-methyl-1,4-diazepan-1-yl)benzamide (Darexaban, YM150) as a Potent and Orally Available Factor Xa Inhibitor

Hirayama, Fukushi, Koshio, Hiroyuki, Ishihara, Tsukasa, Hachiya, Shunichiro, Sugasawa, Keizo, Koga, Yuji, Seki, Norio, Shiraki, Ryouta, Shigenaga, Takeshi, Iwatsuki, Yoshiyuki, Moritani, Yumiko, Mori,

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.33 MB

english, 2011

6

Mechanism of regulation of deoxythymidine kinase of Escherichia coli

Iwatsuki, Norio, Okazaki, Reiji

Journal:

Journal of Molecular Biology

Year:

1967

Language:

english

File:

PDF, 1.12 MB

english, 1967

7

Mechanism of DNA chain growth

Iwatsuki, Norio, Okazaki, Reiji

Journal:

Journal of Molecular Biology

Year:

1970

Language:

english

File:

PDF, 592 KB

english, 1970

8

Mechanism of regulation of deoxythymidine kinase of Escherichia coli

Iwatsuki, Norio, Okazaki, Reiji

Journal:

Journal of Molecular Biology

Year:

1967

Language:

english

File:

PDF, 722 KB

english, 1967

9

Evidence that deoxyribonucleic acid photolyase from bakers' yeast is a flavoprotein

Iwatsuki, Norio, Cheol, O. Joe, Werbin, Harold

Journal:

Year:

1980

Language:

english

File:

PDF, 600 KB

english, 1980

10

Changes of Cyanide Content and Linamarase Activity in Wounded Cassava Roots

Mineo Kojima, Norio Iwatsuki, Emma S. Data, Cynthia Dolores V. Villegas and Ikuzo Uritani

Journal:

PLANT PHYSIOLOGY

Year:

1983

Language:

english

File:

PDF, 701 KB

english, 1983

11

Partial Purification and Characterization of Polyphenol Oxidase Isozymes in Banana Bud

Ôba, Kazuko, Iwatsuki, Norio, Uritani, Ikuzo, Alvarez, Angelina M., Garcia, Virgilio V.

Journal:

Bioscience Biotechnology and Biochemistry

Year:

1992

Language:

english

File:

PDF, 843 KB

english, 1992

12

Early gastric cancer metastasizing to the rectum, possibly via a hematogenous route: a case report and review of literature

Uemura, Norio, Kurashige, Junji, Kosumi, Keisuke, Iwatsuki, Masaaki, Yamashita, Kohei, Iwagami, Shiro, Baba, Yoshifumi, Sakamoto, Yasuo, Miyamoto, Yuji, Yoshida, Naoya, Honda, Yumi, Mikami, Yoshiki, B

Journal:

Surgical Case Reports

Year:

2016

Language:

english

File:

PDF, 1.32 MB

english, 2016

13

Subtypes of Muscarinic Receptors in Pancreatic Exocrine Secretion in Anesthetized Dog

Iwatsuki, Kazuhiko, Horiuchi, Akira, Yonekura, Hiroaki, Homma, Norio, Haruta, Kouichi, Chiba, Shigetoshi

Journal:

Year:

1989

Language:

english

File:

PDF, 561 KB

english, 1989

14

Central α2 Adrenoceptor-Mediated Pancreatic Exocrine Response to Yohimbine in Anesthetized Dog

Iwatsuki, Kazuhiko, Horiuchi, Akira, Haruta, Kouichi, Homma, Norio, Chiba, Shigetoshi

Journal:

Year:

1987

Language:

english

File:

PDF, 451 KB

english, 1987

15

Analysis of a Magnesium-containing: β-Eucryptite Solid Solution by the Lattice Constant Method and Its Application

Iwatsuki, Masaaki, Tsukada, Norio, Fukasawa, Tsutomu

Journal:

Bulletin of the Chemical Society of Japan

Year:

1975

File:

PDF, 797 KB

1975

16

Effects of DN-9693, a synthesized phosphodiesterase inhibitor, on pancreatic exocrine secretion in dogs.

IWATSUKI, Kazuhiko, HORIUCHI, Akira, YONEKURA, Hiroaki, HARUTA, Kouichi, HOMMA, Norio, CHIBA, Shigetoshi

Journal:

The Japanese Journal of Pharmacology

Year:

1989

Language:

english

File:

PDF, 453 KB

english, 1989

17

Effects of synthesized phosphodiesterase inhibitors, DM 9278 and HWA 285, on pancreatic exocrine secretion of the dog.

YAMAGISHI, Fujio, HOMMA, Norio, HARUTA, Kohichi, IWATSUKI, Kazuhiko, CHIBA, Shigetoshi

Journal:

The Japanese Journal of Pharmacology

Year:

1985

Language:

english

File:

PDF, 312 KB

english, 1985

18

Effect of Ivory Shell Toxin on the Parasympathetic Ganglia of the Dog Urinary Bladder

TAIRA, NORIO, IWATSUKI, KAZUHIKO, HASHIMOTO, KOROKU, HIRAYAMA, HACHIHIKO

Journal:

The Tohoku Journal of Experimental Medicine

Year:

1972

Language:

english

File:

PDF, 116 KB

english, 1972

19

Molecular and phylogenetic analyses of the haemagglutinin (H) proteins of field isolates of canine distemper virus from naturally infected dogs

Iwatsuki, Kiyoko, Miyashita, Naoko, Yoshida, Emi, Gemma, Tsuyoshi, Shin, Yeon Sil, Mori, Takeshi, Hirayama, Norio, Kai, Chieko, Mikami, Takeshi

Journal:

Journal of General Virology

Year:

1997

Language:

english

File:

PDF, 584 KB

english, 1997

20

Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7

Yamasaki, Tokiwa, Deki-Arima, Norie, Kaneko, Asahito, Miyamura, Norio, Iwatsuki, Mamiko, Matsuoka, Masato, Fujimori-Tonou, Noriko, Okamoto-Uchida, Yoshimi, Hirayama, Jun, Marth, Jamey D., Yamanashi, Y

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 2.37 MB

english, 2017

21

A complete rat serum albumin cDNA clone directly identified by immunological screening of cDNA expression library.

IWATSUKI, Norio, HATTORI, Tsukaho, IWASAKI, Yukimoto, NAKANO, Masatoshi, NAKAMURA, Kenzo

Journal:

Agricultural and Biological Chemistry

Year:

1987

Language:

english

File:

PDF, 1.01 MB

english, 1987

22

Purification and properties of two enzymes hydrolyzing synthetic substrates, N-.ALPHA.-benzoyl-D,L-arginine p-nitroanilide and leucine p-nitroanilide, from pea seeds.

TOMOMATSU, Atsunobu, IWATSUKI, Norio, ASAHI, Tadasi

Journal:

Agricultural and Biological Chemistry

Year:

1978

Language:

english

File:

PDF, 611 KB

english, 1978

23

The Marmoset as an Animal Model of Influenza: Infection With A(H1N1)pdm09 and Highly Pathogenic A(H5N1) Viruses via the Conventional or Tracheal Spray Route

Iwatsuki-Horimoto, Kiyoko, Nakajima, Noriko, Kiso, Maki, Takahashi, Kenta, Ito, Mutsumi, Inoue, Takashi, Horiuchi, Machiko, Okahara, Norio, Sasaki, Erika, Hasegawa, Hideki, Kawaoka, Yoshihiro

Journal:

Frontiers in Microbiology

Year:

2018

Language:

english

File:

PDF, 3.74 MB

english, 2018

24

ChemInform Abstract: STUDY ON APPLICATION OF LATTICE CONSTANT MEASUREMENT BY X-RAY DIFFRACTION METHOD TO THE ANALYSIS OF INDUSTRIAL MATERIALS PART 4, ANALYSIS OF A MAGNESIUM-CONTAINING BETA-EUCRYPTITE SOLID SOLUTION BY THE LATTICE CONSTANT METHOD AND ITS

IWATSUKI, MASAAKI, TSUKADA, NORIO, FUKASAWA, TSUTOMU

Journal:

Chemischer Informationsdienst

Year:

1975

File:

PDF, 128 KB

1975

25

The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner

Yamamoto, Mizuki, Kiso, Maki, Sakai-Tagawa, Yuko, Iwatsuki-Horimoto, Kiyoko, Imai, Masaki, Takeda, Makoto, Kinoshita, Noriko, Ohmagari, Norio, Gohda, Jin, Semba, Kentaro, Matsuda, Zene, Kawaguchi, Yas

Journal:

Year:

2020

File:

PDF, 924 KB

2020

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